Lobophorin CR-2
Lobophorin CR-2 is a lobophorin congener which induces UPR-associated gene expression, inhibits oral squamous cell carcinoma cell growth, and causes UPR-dependent cell death in MEF cells[1].
Product Specifications
CAS Number
1800562-59-7
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lobophorin-cr-2.html
Solubility
10 mM in DMSO
Smiles
OC([C@@]12[C@@](/C=C([C@H](CC(C([C@@]3([H])[C@@]4([C@@]5([H])[C@@](C=C3)([H])[C@H]([C@H](C[C@@H]5C)C)O[C@H]6C[C@H]([C@H]([C@@H](O6)C)O)O[C@H]7C[C@H]([C@H]([C@@H](O7)C)O[C@@H]8C[C@H]([C@H]([C@@H](O8)C)OC)O)O)C)=C)O)O[C@H]9C[C@@](C)([C@H]([C@H](O9)C)NC(OC)=O)[N+]([O-])=O)\C)([H])C=C([C@@H](C1)C)CO)=C(C(O2)=O)C4=O
Molecular Formula
C61H90N2O22
Molecular Weight
1203.37
References & Citations
[1]Cruz PG, et al. Novel Lobophorins Inhibit Oral Cancer Cell Growth and Induce Atf4- and Chop-Dependent Cell Death in Murine Fibroblasts. ACS Med Chem Lett. 2015 Jul 6;6 (8) :877-81.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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