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Phosphorylcholine (chloride)

Phosphorylcholine chloride (Phosphocholine chloride) is the main phospholipid component in eukaryotic biofilms. Phosphorylcholine chloride exists in commensal or pathogenic bacteria associated with eukaryotes in prokaryotes. Phosphorylcholine chloride exhibits a surprising range of immunomodulatory properties[1].

Product Specifications

CAS Number

107-73-3

Product Name Alternative

Phosphocholine (chloride)

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor; Endogenous Metabolite

Type

Reference compound

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Applications

COVID-19-anti-virus

Field of Research

Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/Phosphorylcholine.html

Concentration

10mM

Purity

98.02

Solubility

H2O : 250 mg/mL (ultrasonic)

Smiles

O=P(OCC[N+](C)(C)C)(O)O.[Cl-]

Molecular Formula

C5H15ClNO4P

Molecular Weight

219.60

Precautions

H302, H315, H319, H335

References & Citations

[1]Lawton JM, et al. The effect of cationically-modified phosphorylcholine polymers on human osteoblasts in vitro and their effect on bone formation in vivo. J Mater Sci Mater Med. 2017 Aug 17;28 (9) :144.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite; Microbial Metabolite

Citation 01

J Physiol Biochem. 2022 May;78 (2) :355-363.|Adv Sci (Weinh) . 2024 Dec 4:e2411276.|Anal Chem. 2025 May 13;97 (18) :9827-9835.|JCI Insight. 2021 Oct 22;6 (20) :e151911.|Nat Commun. 2023 Mar 24;14 (1) :1631.|Nature. 2025 Jul;643 (8070) :192-200.|NPJ Biofilms Microbiomes. 2023 Sep 4;9 (1) :62.|Patent. US20250160318A1.|Virulence. 2025 Dec;16 (1) :2490208.

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