Antitumor agent-119

Antitumor agent-119 (compound 13K) is a 2-benzoxazolyl hydrazone derivative with anticancer activities. Antitumor agent-119 inhibits the cell growth of Butkitt, CCRF-CEM, HeLa, and HT-29 with IC50 values of 30 nM, 140 nM, 100 nM, and 40 nM, respectively[1].

Product Specifications

CAS Number

[913169-79-6]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-119.html

Purity

98.03

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C/C(C1=CC2=C(C=CC=C2)C=N1)=N\NC3=NC4=CC=CC=C4O3

Molecular Formula

C18H14N4O

Molecular Weight

302.34

Precautions

H302, H315, H319, H335

References & Citations

[1]N. S. Hari Narayana Moorthy, et al. QSAR analysis of 2-benzoxazolyl hydrazone derivatives for anticancer activity and its possible target prediction. Med Chem Res 21, 133–144 (2012) .