Mal-C2-cyclohexylcarboxyl-hydrazide (hydrochloride)

Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

[174422-72-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mal-c2-cyclohexylcarboxyl-hydrazide-hydrochloride.html

Purity

98.23

Solubility

DMSO : 16.67 mg/mL (ultrasonic) |H2O : 33.33 mg/mL (ultrasonic)

Smiles

Cl[H].O=C1C=CC(N1CC(CC2)CCC2C(NN)=O)=O

Molecular Formula

C12H18ClN3O3

Molecular Weight

287.74

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl-Chain Linkers

Available Sizes

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