5-Nitro-1,10-phenanthroline

5-Nitro-1,10-phenanthroline (5-NP), is a o-Phenanthroline (HY-W004544) derivative, as a mediator of glucose oxidase (GOX) with antituberculous activity. 5-Nitro-1,10-phenanthroline can be applied as redox mediators for oxidases and is suitable for the development of reagent-less biosensors and biofuel cells[1][1].

Product Specifications

CAS Number

[4199-88-6]

Product Name Alternative

5-NP

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/5-nitro-1-10-phenanthroline.html

Purity

99.88

Solubility

DMSO : 35 mg/mL (ultrasonic) |Ethanol : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=[N+]([O-])C1=C2C(N=CC=C2)=C3C(C=CC=N3)=C1

Molecular Formula

C12H7N3O2

Molecular Weight

225.21

Precautions

H315, H319, H335

References & Citations

[1]Oztekin Y, et al. 1,10-Phenanthroline derivatives as mediators for glucose oxidase. Biosens Bioelectron. 2010 Sep 15;26 (1) :267-70. |[2]Kidwai S, et al. Dual Mechanism of Action of 5-Nitro-1,10-Phenanthroline against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 2017 Oct 24;61 (11) :e00969-17.