Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

NLS-StAx-h

NLS-StAx-h is a selective, cell permeable, stapled peptide Wnt signaling inhibitor with an IC50 of 1.4 μM. NLS-StAx-h efficiently inhibits β-catenin-transcription factor interactions. NLS-StAx-h shows anti-proliferation of cancer cells[1][2].

Product Specifications

CAS Number

2872559-21-0

UNSPSC

12352209

Target

Wnt; β-catenin

Type

Peptides

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nls-stax-h.html

Solubility

10 mM in DMSO

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](CCCCNC(N)=N)C(N[C@@]2(C(N[C@@](C(N[C@H](C(N[C@H](C(N[C@@](C)(CCC/C=C/CCC2)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](CCCCNC(N)=N)C(N[C@@H](CCCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@H](C(N[C@H](C(N)=O)CCCCNC(N)=N)=O)CC3=CNC4=CC=CC=C34)=O)=O)=O)=O)=O)CC5=CN=CN5)=O)=O)CC(O)=O)=O)CC(C)C)=O)([H])[C@@H](C)CC)=O)C)=O)=O)[C@@H](NC([C@H](CCCCNC(N)=N)NC([C@H](CCCCNC(N)=N)NC(COCCOCCNC([C@H](C(C)C)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@@H]6CCCN6)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC7=CNC8=CC=CC=C78

Molecular Formula

C161H275N55O29

Molecular Weight

3445.25

References & Citations

[1]Laura Dietrich, et al. Cell Permeable Stapled Peptide Inhibitor of Wnt Signaling That Targets β-Catenin Protein-Protein Interactions|[2]ang Z, et al. Direct targeting of β-catenin in the Wnt signaling pathway: Current progress and perspectives. Med Res Rev. 2021 Jul;41 (4) :2109-2129.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) (NGFR/1964), CF405S conjugate, 0.1mg/mL
BNC041964-100 1x 100 µL

NGF-Receptor (p75) / CD271 (Soft Tissue Tumor Marker) (NGFR/1964), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Transgelin / SM22-alpha (TAGLN/247), 0.2mg/mL
BNUB0247-500 1x 500 µL

Transgelin / SM22-alpha (TAGLN/247), 0.2mg/mL

Sign In for Pricing
View Details
Uroplakin 1A (Urothelial Differentiation Marker) (UPK1A/2922), CF568 conjugate, 0.1mg/mL
BNC682922-500 1x 500 µL

Uroplakin 1A (Urothelial Differentiation Marker) (UPK1A/2922), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
N-Acetyl-cys(1)-calcitonin Salmon Trifluoroacetic Acid Salt
TRC-A168465-5MG 5 mg

N-Acetyl-cys(1)-calcitonin Salmon Trifluoroacetic Acid Salt

Sign In for Pricing
View Details
Mucin 5AC (MUC5AC) (MUC5AC/917), CF405S conjugate, 0.1mg/mL
BNC040917-100 1x 100 µL

Mucin 5AC (MUC5AC) (MUC5AC/917), CF405S conjugate, 0.1mg/mL

Sign In for Pricing
View Details
HPCAL4 Mouse Monoclonal Antibody [Clone ID: OTI3F11]
CF808692 100 µg

HPCAL4 Mouse Monoclonal Antibody [Clone ID: OTI3F11]

Sign In for Pricing
View Details