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SCH-43478

SCH-43478 is a non-nucleoside antiviral agent. SCH-43478 shows potent and selective activity against herpes simplex virus type 2 (HSV-2) with an IC50 of 1.8 μg/mL using Vero cells. SCH-43478 demonstrates significant efficacy in the guinea pig genital model of HSV infection[1].

Product Specifications

CAS Number

112446-99-8

UNSPSC

12352005

Target

HSV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sch-43478.html

Smiles

CC1=NN=C2NC3=CC=C(OC)C=C3C(Cl)=C21

Molecular Formula

C12H10ClN3O

Molecular Weight

247.68

References & Citations

[1]R Albin, et al. SCH 43478 and analogs: in vitro activity and in vivo efficacy of novel agents for herpesvirus type 2. Antiviral Res. 1997 Aug;35 (3) :139-46.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HSV-2

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