SCH-43478
SCH-43478 is a non-nucleoside antiviral agent. SCH-43478 shows potent and selective activity against herpes simplex virus type 2 (HSV-2) with an IC50 of 1.8 μg/mL using Vero cells. SCH-43478 demonstrates significant efficacy in the guinea pig genital model of HSV infection[1].
Product Specifications
CAS Number
112446-99-8
UNSPSC
12352005
Target
HSV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sch-43478.html
Smiles
CC1=NN=C2NC3=CC=C(OC)C=C3C(Cl)=C21
Molecular Formula
C12H10ClN3O
Molecular Weight
247.68
References & Citations
[1]R Albin, et al. SCH 43478 and analogs: in vitro activity and in vivo efficacy of novel agents for herpesvirus type 2. Antiviral Res. 1997 Aug;35 (3) :139-46.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSV-2
Frequently Asked Questions
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