Teprasiran
Teprasiran (QPI-1002) is a small interfering RNA that temporarily inhibits p53-mediated cell death that underlies acute kidney injury (AKI) [1].
Product Specifications
CAS Number
[1231737-88-4]
Product Name Alternative
QPI-1002
UNSPSC
12352208
Target
MDM-2/p53; Small Interfering RNA (siRNA)
Type
Oligonucleotides
Related Pathways
Apoptosis; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/teprasiran.html
Purity
90.25
Solubility
H2O : ≥ 20 mg/mL
Smiles
[Teprasiran]
Molecular Formula
C380H484N140O262P36
Molecular Weight
12320.00
References & Citations
[1]Matthias Thielmann, et al. Teprasiran, a Small Interfering RNA, for the Prevention of Acute Kidney Injury in High-Risk Patients Undergoing Cardiac Surgery: A Randomized Clinical Study. Circulation. 2021;144:1133-1144.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
Phase 3
Available Sizes
Curated Selection
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