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Ramatroban

Ramatroban is a selective thromboxane A2 (TxA2, IC50=14 nM) antagonist, which also antagonizes CRTH2 (IC50=113 nM) by inhibiting PGD2 binding.

Product Specifications

CAS Number

116649-85-5

Product Name Alternative

BAY u3405

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Endocrinology; Cancer

Assay Protocol

https://www.medchemexpress.com/Ramatroban.html

Purity

99.10

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(O)CCN1C2=C(C3=C1C=CC=C3)C[C@H](NS(=O)(C4=CC=C(F)C=C4)=O)CC2

Molecular Formula

C21H21FN2O4S

Molecular Weight

416.47

Precautions

H302, H315, H319, H335

References & Citations

222

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

DP; TXA2/TP

Available Sizes

Frequently Asked Questions

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