Ramatroban
Ramatroban is a selective thromboxane A2 (TxA2, IC50=14 nM) antagonist, which also antagonizes CRTH2 (IC50=113 nM) by inhibiting PGD2 binding.
Product Specifications
CAS Number
[116649-85-5]
Product Name Alternative
BAY u3405
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology; Cancer
Assay Protocol
https://www.medchemexpress.com/Ramatroban.html
Purity
99.10
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(O)CCN1C2=C(C3=C1C=CC=C3)C[C@H](NS(=O)(C4=CC=C(F)C=C4)=O)CC2
Molecular Formula
C21H21FN2O4S
Molecular Weight
416.47
Precautions
H302, H315, H319, H335
References & Citations
222
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
DP; TXA2/TP
Available Sizes
Curated Selection
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