DL-Homocysteine

DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. DL-Homocysteine is correlated with Vitamin B12, renal functions and folate levels, affects the cross-sectional cognition indirectly through white matter microstructural integrity[2].

Product Specifications

CAS Number

[454-29-5]

UNSPSC

12352211

Hazard Statement

H410

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/2-Amino-4-mercaptobutanoic_acid.html

Concentration

10mM

Purity

99.32

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

O=C(O)C(N)CCS

Molecular Formula

C4H9NO2S

Molecular Weight

135.19

Precautions

H410

References & Citations

[1]DL-Homocysteine, et al. Dual effect of DL-homocysteine and S-adenosylhomocysteine on brain synthesis of the glutamate receptor antagonist, kynurenic acid. J Neurosci Res. 2005 Feb 1;79 (3) :375-82.|[2]Effects of Homocysteine on white matter diffusion parameters in Alzheimer’s disease