HCTZ-CH2-HCTZ
HCTZ-CH2-HCTZ is an isomer of HCTZ. Hydrochlorothiazide (HCTZ), an orally active diuretic agent of the thiazide class, inhibits transforming TGF-β/Smad signaling pathway[1][2].
Product Specifications
CAS Number
402824-96-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Intermediate; TGF-β Receptor
Type
Reference compound
Related Pathways
Others; TGF-beta/Smad
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/hctz-ch2-hctz.html
Smiles
O=S(N)(C1=C(Cl)C=C(N(CNS2(=O)=O)CNS(=O)(C3=C(Cl)C=C(NCNS4(=O)=O)C4=C3)=O)C2=C1)=O
Molecular Formula
C15H16Cl2N6O8S4
Molecular Weight
607.49
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Duarte, J.D. and R.M. Cooper-DeHoff, Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics. Expert Rev Cardiovasc Ther, 2010. 8 (6) : p. 793-802.|[2]X Fang, et al. Purification and identification of an impurity in bulk hydrochlorothiazide. J Pharm Sci. 2001 Nov;90 (11) :1800-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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