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(R, R) -Secoisolariciresinol diglucoside-d6

(R, R) -Secoisolariciresinol diglucoside-d6 is deuterated labeled (R, R) -Secoisolariciresinol diglucoside. (R, R) -Secoisolariciresinol diglucoside ((R, R) -SDG) is the minor isomer of Secoisolariciresinol diglucoside in flaxseed. (R, R) -Secoisolariciresinol diglucoside ((R, R) -SDG) possesses antioxidant and free radical scavenging activities and DNA-radioprotective properties. (R, R) -Secoisolariciresinol diglucoside ((R, R) -SDG) inhibits myeloperoxidase (MPO) activity by suppressing both the peroxidase and chlorination cyclesin inflammatory cells[1][2][3].

Product Specifications

Product Name Alternative

(R, R) -SDG-d6; (R, R) -LGM2605-d6

UNSPSC

12352005

Target

Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=C(OC([2H])([2H])[2H])C=C1C[C@@H](CO[C@@H]2O[C@@H]([C@H]([C@@H]([C@H]2O)O)O)CO)[C@H](CO[C@@H]3O[C@@H]([C@H]([C@@H]([C@H]3O)O)O)CO)CC4=CC(OC([2H])([2H])[2H])=C(C=C4)O

Molecular Formula

C32H40D6O16

Molecular Weight

692.74

References & Citations

[1]Mishra OP, et al. Novel synthetic (S, S) and (R, R) -secoisolariciresinol diglucosides (SDGs) protect naked plasmid and genomic DNA From gamma radiation damage. Radiat Res. 2014 Jul;182 (1) :102-10.|[2]Mishra OP, et al. Synthesis and antioxidant evaluation of (S, S) - and (R, R) -secoisolariciresinol diglucosides (SDGs) . Bioorg Med Chem Lett. 2013 Oct 1;23 (19) :5325-8.|[3]Mishra OP, et al. Synthetic secoisolariciresinol diglucoside (LGM2605) inhibits myeloperoxidase activity in inflammatory cells. Biochim Biophys Acta Gen Subj. 2018 Jun;1862 (6) :1364-1375.|[4]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Frequently Asked Questions

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