Fmoc-NH-PEG9-CH2CH2COOH
Fmoc-NH-PEG9-CH2CH2COOH is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) . Fmoc-NH-PEG9-CH2CH2COOH is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Product Specifications
CAS Number
[1191064-81-9]
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker; PROTAC Linkers
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-nh-peg9-ch2ch2cooh.html
Purity
98.21
Solubility
10 mM in DMSO
Smiles
O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
Molecular Formula
C36H53NO13
Molecular Weight
707.80
Precautions
H302, H315, H319, H335
References & Citations
[1]Yang Y, et al. Design, synthesis, and biological characterization of novel PEG-linked dimeric modulators for CXCR4. Bioorg Med Chem. 2016 Nov 1;24 (21) :5393-5399.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
ADC Related
Clinical Information
No Development Reported
Isoform
Cleavable Linker; PEG Linkers
Available Sizes
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