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15α-Hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α (6,11α) -diolide

Selected Variant

HY-N12135-01

Size: 1 mg

15α-Hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α (6,11α) -diolide (compound 2) is an enantio-kaurene diterpenoid (ent -kaurene diterpenoid), which can be isolated from Rubescens rubescens. 15α-Hydroxy-20-oxo-6,7-seco-ent-kaur-16-en-1,7α (6,11α) -diolide has cellular activity against EC-1, U87, A549, MCF-7 and HeLa cell lines Toxicity, IC50s are 37.69 μM, 79.362 μM, 80.07 μM, 197.35 μM, 462.13 μM, and 180.09 μM respectively[1].

Product Specifications

CAS Number

1355450-84-8

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/15α-hydroxy-20-oxo-6-7-seco-ent-kaur-16-en-1-7α-6-11α-diolide.html

Solubility

10 mM in DMSO

Smiles

O=C[C@]([C@@]1([H])C2(C)C)([C@@](CC2)([H])OC3=O)[C@@]4([H])[C@]3([C@@H](C5=C)O)C[C@@]5([H])C[C@]4([H])OC1=O

Molecular Formula

C20H24O6

Molecular Weight

360.40

References & Citations

[1]Xie RJ, et al. Two new diterpenoids and other constituents from Isodon rubescens. Fitoterapia. 2011 Jun;82 (4) :726-30.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

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