Argifin
Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively[1].
Product Specifications
CAS Number
243975-37-3
UNSPSC
12352209
Target
Parasite
Type
Peptides
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/argifin.html
Purity
99.90
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CN(C([C@@H](NC([C@H](NC1=O)C)=O)CCCNC(NC(NC)=O)=N)=O)[C@H](C(N[C@@H](CC(N[C@@H](C1)C(O)=O)=O)C(O)=O)=O)CC2=CC=CC=C2
Molecular Formula
C29H41N9O10
Molecular Weight
675.69
References & Citations
[1]Hirose T, et al. Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms. Proc Jpn Acad Ser B Phys Biol Sci. 2010;86 (2) :85-102.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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