Argifin

Argifin is a sub-nanomolar chitinase inhibitor produced by soil microorganisms, with IC50s of 0.025 μM, 6.4 μM , 1.1 μM and 4.5 μM for SmChiA (Serratia marcescens chitinaese A), SmChiB, Aspergillus fumigatus chitinase B1 and human chitotriosidase, respectively[1].

Product Specifications

CAS Number

[243975-37-3]

UNSPSC

12352209

Target

Parasite

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/argifin.html

Purity

99.90

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CN(C([C@@H](NC([C@H](NC1=O)C)=O)CCCNC(NC(NC)=O)=N)=O)[C@H](C(N[C@@H](CC(N[C@@H](C1)C(O)=O)=O)C(O)=O)=O)CC2=CC=CC=C2

Molecular Formula

C29H41N9O10

Molecular Weight

675.69

References & Citations

[1]Hirose T, et al. Recent development of two chitinase inhibitors, Argifin and Argadin, produced by soil microorganisms. Proc Jpn Acad Ser B Phys Biol Sci. 2010;86 (2) :85-102.