Cav 2.2 blocker 1
Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM[1].
Product Specifications
CAS Number
[1567335-29-8]
UNSPSC
12352005
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cav-2-2-blocker-1.html
Purity
99.38
Solubility
DMSO : 20.83 mg/mL (ultrasonic)
Smiles
COC(C=CC=C1)=C1N2C(C3=CC=C(Cl)C=C3)=CC(C4CC(C)(C)OC(C)(C)C4)=N2
Molecular Formula
C25H29ClN2O2
Molecular Weight
424.96
References & Citations
[1]Wall MJ, et al. Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain. Bioorg Med Chem Lett. 2018 Dec 15;28 (23-24) :3780-3783.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
036625-Biotin 200 µL
HLA-DRB4, NT (HLA-DRB4, HLA class II histocompatibility antigen, DR beta 4 chain, MHC class II antigen DRB4) (Biotin) discontinued
Ask
View Details 53831151 3x 1.0 µg DNA
C6orf208 CRISPR All-in-one AAV vector set (with saCas9)(Human)
Ask
View Details 