Cav 2.2 blocker 1
Product Specifications
UNSPSC Description
Cav 2.2 blocker 1 (compound 9) is a N-type calcium channel (Cav 2.2) blocker for the treatment of pain, with an IC50 of 1 nM[1].
Target Antigen
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/cav-2-2-blocker-1.html
Purity
99.38
Solubility
DMSO : 20.83 mg/mL (ultrasonic)
Smiles
COC(C=CC=C1)=C1N2C(C3=CC=C(Cl)C=C3)=CC(C4CC(C)(C)OC(C)(C)C4)=N2
Molecular Weight
424.96
References & Citations
[1]Wall MJ, et al. Discovery and optimization of a novel series of pyrazolyltetrahydropyran N-type calcium channel (Cav 2.2) blockers for the treatment of pain. Bioorg Med Chem Lett. 2018 Dec 15;28(23-24):3780-3783.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119373/Cav-2-2-blocker-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119373/Cav-2-2-blocker-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1567335-29-8
Available Sizes
Curated Selection
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