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CST967

CST967 (Compound 17) is a USP7 PROTAC degrader, and increasing the PROTAC concentration can enhance the degradation rate of USP7. CST967 can be used in cancer research[1].

Product Specifications

UNSPSC

12352005

Target

PROTACs

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cst967.html

Purity

99.33

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N(C1CCC(NC1=O)=O)C2=O)C(C2=C3)=CC=C3N4CCC(C(N5CCC(CCC(NC6=CC=C7C(N=CN(CC8(O)CCN(C(C[C@@H](C)C9=CC=CC=C9)=O)CC8)C7=O)=C6)=O)CC5)=O)CC4

Molecular Formula

C51H58N8O9

Molecular Weight

927.05

References & Citations

[1]Murgai, et al. "Targeting the deubiquitinase USP7 for degradation with PROTACs." Chemical Communications 58.63 (2022) : 8858-8861.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-160502/CST967-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-160502/CST967-SDS-MedChemExpress.pdf

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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