IDT

IDT is a safe and effective TNFα and innate immune system modulator. IDT significantly reduced paired helical filament tau and fibrillar amyloid accumulation and increased the infiltrating neutrophil population while reducing TNFα expression in this population. IDT can be used in Alzheimer's disease research[1].

Product Specifications

CAS Number

[18138-19-7]

UNSPSC

12352005

Target

Tau Protein; TNF Receptor

Type

Reference compound

Related Pathways

Apoptosis; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/idt.html

Smiles

S=C1NC(C2=C1C=CC=C2)=S

Molecular Formula

C8H5NS2

Molecular Weight

179.26

References & Citations

[1]Gabbita S P, et al. Oral TNFα modulation alters neutrophil infiltration, improves cognition and diminishes tau and amyloid pathology in the 3xTgAD mouse model[J]. PLoS One, 2015, 10 (10) : e0137305.