IDT
Product Specifications
UNSPSC Description
IDT is a safe and effective TNFα and innate immune system modulator. IDT significantly reduced paired helical filament tau and fibrillar amyloid accumulation and increased the infiltrating neutrophil population while reducing TNFα expression in this population. IDT can be used in Alzheimer's disease research[1].
Target Antigen
Tau Protein; TNF Receptor
Type
Reference compound
Related Pathways
Apoptosis;Neuronal Signaling
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/idt.html
Smiles
S=C1NC(C2=C1C=CC=C2)=S
Molecular Weight
179.26
References & Citations
[1]Gabbita S P, et al. Oral TNFα modulation alters neutrophil infiltration, improves cognition and diminishes tau and amyloid pathology in the 3xTgAD mouse model[J]. PLoS One, 2015, 10(10): e0137305.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-116426/IDT-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-116426/
Clinical Information
Phase 2
CAS Number
18138-19-7
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