Nalidixic acid (sodium salt)
Nalidixic acid sodium salt, a quinolone antibiotic, is effective against both gram-positive and gram-negative bacteria. Nalidixic acid acts in a bacteriostatic manner in lower concentrations and is bactericidal in higher concentrations. Nalidixic acid inhibits a subunit of DNA gyrase and topoisomerase IV and reversibly blocks DNA replication in susceptible bacteria[1][2].
Product Specifications
CAS Number
3374-05-8
UNSPSC
12352005
Hazard Statement
H302, H317, H334
Target
Antibiotic; Bacterial; Topoisomerase
Type
Reference compound
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/nalidixic-acid-sodium-salt.html
Purity
99.83
Solubility
H2O : 116.67 mg/mL (ultrasonic)
Smiles
O=C(C1=CN(CC)C2=NC(C)=CC=C2C1=O)O[Na]
Molecular Formula
C12H11N2NaO3
Molecular Weight
254.22
Precautions
H302, H317, H334
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Quinolone; Topoisomerase
Available Sizes
Frequently Asked Questions
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