3′-Deoxy-3′-fluorouridine
3′-Deoxy-3′-fluorouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[57944-13-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H320, H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others; Cancer
Assay Protocol
https://www.medchemexpress.com/3-deoxy-3-fluorouridine.html
Purity
99.66
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@H](F)[C@@H](CO)O[C@H]1N2C(NC(C=C2)=O)=O
Molecular Formula
C9H11FN2O5
Molecular Weight
246.19
Precautions
H302, H315, H320, H335
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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