STO-609
STO-609 is a selective and cell-permeable inhibitor of the Ca2+/calmodulin-dependent protein kinase kinase (CaM-KK), with Ki values of 80 and 15 ng/mL for recombinant CaM-KKα and CaM-KKβ, respectively. STO-609 inhibits AMP-activated protein kinase kinase (AMPKK) activity in HeLa cell lysates with an IC50 ~0.02 g/ml.
Product Specifications
CAS Number
[52029-86-4]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
AMPK; Autophagy; CaMK
Type
Reference compound
Related Pathways
Autophagy; Epigenetics; Neuronal Signaling; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/STO-609.html
Concentration
10mM
Purity
98.20
Smiles
O=C(C1=C2C3=C(C4=NC5=CC=CC=C5N4C(C3=CC=C2)=O)C=C1)O
Molecular Formula
C19H10N2O3
Molecular Weight
314.29
Precautions
H302, H315, H319, H335
References & Citations
2+
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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