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Linoleic acid-d4

Linoleic Acid-d4 is the deuterium labeled Linoleic acid. Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism [1][2].

Product Specifications

CAS Number

[79050-23-0]

UNSPSC

12352211

Hazard Statement

H225, H319, H336

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease; Cardiovascular Disease

Concentration

17.58 mM * 99.98 μL in Methyl acetate

Purity

99.79

Solubility

10 mM in DMSO

Smiles

CCCCC/C([2H])=C(C/C([2H])=C(CCCCCCCC(O)=O)/[2H])/[2H]

Molecular Formula

C18H28D4O2

Molecular Weight

284.47

Precautions

H225, H319, H336

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Jay Whelan. Linoleic Acid. Adv Nutr. 2013 May; 4 (3) : 311–312.|[3]Yuan T, et al. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism. Int J Clin Exp Pathol. 2015 May 1;8 (5) :5044-52.

Shipping Conditions

Blue Ice

Storage Conditions

Solution, -20°C, 2 years

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

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