EEDi-5273
Product Specifications
Product Name Alternative
APG-5918
UNSPSC Description
EEDi-5273 is an exceptionally potent and orally efficacious EED inhibitor (IC50 = 0.2 nM) capable of achieving complete and persistent tumor regression.
Target Antigen
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eedi-5273.html
Purity
99.09
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CC(N1CC2=CC(C(F)(F)F)=NC=C2C3=CN=C(N4C=NC(C1=O)=C34)NCC5=C6CCOC6=CC=C5F)C
Molecular Weight
526.49
References & Citations
[1]Rej RK, et al. Discovery of EEDi-5273 as an Exceptionally Potent and Orally Efficacious EED Inhibitor Capable of Achieving Complete and Persistent Tumor Regression. J Med Chem. 2021 Oct 14;64(19):14540-14556.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-132922/EEDi-5273-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-132922/EEDi-5273-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
2585648-55-9
Available Sizes
Curated Selection
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