N-myristoyl-RKRTLRRL
Product Specifications
UNSPSC Description
N-myristoyl-RKRTLRRL inhibits binding of PKC substrates. N-myristoyl-RKRTLRRL inhibits Ca2+- and phosphatidylserine (PS)-dependent histone phosphorylation with IC50 of 5 μM. histone phosphorylation with IC50 of 80 μM[1][2].
Target Antigen
PKC
Type
Peptides
Related Pathways
Epigenetics;TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
cancer
Assay Protocol
https://www.medchemexpress.com/n-myristoyl-rkrtlrrl.html
Purity
99.37
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC(C)C[C@@H](C(O)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@H](CCCNC(N)=N)NC([C@H](CCCCN)NC([C@H](CCCNC(N)=N)NC(CCCCCCCCCCCCC)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
1308.71
References & Citations
[1]David K Crockett, et al. Identification of proteins from formalin-fixed paraffin-embedded cells by LC-MS/MS. Lab Invest. 2005 Nov;85(11):1405-15.|[2]C A O'Brian, et al. A novel N-myristylated synthetic octapeptide inhibits protein kinase C activity and partially reverses murine fibrosarcoma cell resistance to Adriamycin. Invest New Drugs. 1991 May;9(2):169-79.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P5988/N-myristoyl-RKRTLRRL-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P5988/N-myristoyl-RKRTLRRL-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
152246-40-7
Available Sizes
Curated Selection
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