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Ent-Florfenicol-d3

Ent-Florfenicol-d3 is the deuterium labeled Florfenicol. Florfenicol, a commonly used veterinary antibiotic, is currently indicated for the treatment of bovine respiratory disease, and also used in aquaculture for the control of enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g.

Product Specifications

CAS Number

1217619-10-7

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection

Field of Research

Infection

Solubility

10 mM in DMSO

Smiles

[C@@H]([C@](NC(C(Cl)Cl)=O)(C(F)([2H])[2H])[2H])(O)C1=CC=C(S(C)(=O)=O)C=C1

Molecular Formula

C12H11D3Cl2FNO4S

Molecular Weight

361.23

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Al-Shahrani S, et al. Florfenicol induces early embryonic death in eggs collected from treated hens. BMC Vet Res. 2015 Aug 18;11 (1) :213.|[3]Corinna Kehrenberg, et al. A new mechanism for chloramphenicol, florfenicol and clindamycin resistance: methylation of 23S ribosomal RNA at A2503. Molecular Microbiology
 Volume 57, Issue 4, pages 1064–1073, August 2005

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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