Pyrazoloadenine
Product Specifications
UNSPSC Description
Pyrazoloadenine is a potent RET (REarranged during Transfection) lung cancer oncoprotein inhibitor. Pyrazoloadenine shows anticancer activity[1][2].
Target Antigen
RET
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pyrazoloadenine.html
Purity
99.98
Solubility
DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)
Smiles
NC1=C2C(NN=C2)=NC=N1
Molecular Weight
135.13
References & Citations
[1]Saha D, et al. Pyrazoloadenine Inhibitors of the RET Lung Cancer Oncoprotein Discovered by a Fragment Optimization Approach. ChemMedChem. 2021 May 18;16(10):1605-1608.|[2]SKIPPER HE, et al. Inhibition of experimental neoplasms by 4-aminopyrazolo (3, 4-d) pyrimidine. Proc Soc Exp Biol Med. 1955 Aug;89(4):594-6.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-34595/Pyrazoloadenine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-34595/Pyrazoloadenine-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2380-63-4
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
