Hemopressin (rat)

Hemopressin (rat) is a nonapeptide derived from the α1-chain of hemoglobin, is originally isolated from rat brain homogenates. Hemopressin (rat) is orally active, selective and inverse agonist of CB1 cannabinoid receptors. Hemopressin (rat) exerts antinociceptive action in inflammatory pain models[1][2].

Product Specifications

CAS Number

[568588-77-2]

UNSPSC

12352209

Target

Cannabinoid Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hemopressin-rat.html

Purity

99.86

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC([C@H](CC1=CN=CN1)NC([C@H](CO)NC([C@H](CC(C)C)NC([C@@H](NC([C@H](CCCCN)NC([C@@H](NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@@H]2CCCN2)=O)=O)=O)CC3=CC=CC=C3)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O

Molecular Formula

C53H77N13O12

Molecular Weight

1088.26

References & Citations

[1]Camila Squarzoni Dale, et al. Hemopressin: a novel bioactive peptide derived from the alpha1-chain of hemoglobin. em Inst Oswaldo Cruz. 2005 Mar;100 Suppl 1:105-6.|[2]Elaine F Toniolo, et al. Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats. Peptides. 2014 Jun;56:125-31.