Betaxolol (hydrochloride)

Betaxolol Hydrochloride is a selective beta1 adrenergic receptor blocker that can be used for the research of hypertension and glaucoma.

Product Specifications

CAS Number

[63659-19-8]

Product Name Alternative

SL75212

UNSPSC

12352005

Hazard Statement

H302

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/Betaxolol-hydrochloride.html

Concentration

10mM

Purity

99.30

Solubility

DMSO : ≥ 100 mg/mL|H2O : 10 mg/mL (ultrasonic)

Smiles

OC(CNC(C)C)COC1=CC=C(CCOCC2CC2)C=C1.[H]Cl

Molecular Formula

C18H30ClNO3

Molecular Weight

343.89

Precautions

H302

References & Citations

[1]Rudoy, C.A. and E.J. Van Bockstaele, Betaxolol, a selective beta (1) -adrenergic receptor antagonist, diminishes anxiety-like behavior during early withdrawal from chronic cocaine administration in rats. Prog Neuropsychopharmacol Biol Psychiatry, 2007. 31 (5) : p. 1119-29.|[2]Lesar, T.S., Comparison of ophthalmic beta-blocking agents. Clin Pharm, 1987. 6 (6) : p. 451-63.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Citation 01

ACS Biomater Sci Eng. 2022 Nov 14;8 (11) :4850-4862.|Cell Rep Methods. 2023 Oct 23;3 (10) :100599.|Invest Ophthalmol Vis Sci. 2025 Jun 2;66 (6) :13.|Biomacromolecules. 2025 Dec 8;26 (12) :8726-8738.|Chirality. 2018 Nov;30 (11) :1195-1205.|J Pharm Biomed Anal. 2021 Feb 20:195:113870.|Missouri University of Science and Technology. 2025.|Neuron. 2025 Jun 18;113 (12) :1983-1997.e7.