MT-DADMe-ImmA
Product Specifications
UNSPSC Description
MT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP) with a Ki of 90 pM.
Target Antigen
Histone Methyltransferase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/MT-DADMe-ImmA.html
Purity
98.42
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O[C@H]1CN(CC2=CNC3=C(N)N=CN=C32)C[C@@H]1CSC
Molecular Weight
293.396
References & Citations
[1]Evans GB, et al. Second generation transition state analogue inhibitors of human 5'-methylthioadenosine phosphorylase. J Med Chem. 2005 Jul 14;48(14):4679-89.|[2]Basu I, et al. A transition state analogue of 5'-methylthioadenosine phosphorylase induces apoptosis in head and neck cancers. J Biol Chem. 2007 Jul 20;282(29):21477-86.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-101496/MT-DADMe-ImmA-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101496/MT-DADMe-ImmA-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
653592-04-2
Available Sizes
Curated Selection
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