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CGS 20625

Product Specifications

UNSPSC Description

CGS 20625 is a potent, selective and orally active partial agonist for the central benzodiazepine receptor. CGS 20625 inhibits [3H]-flunitrazepam binding to central benzodiazepine receptors with an IC50 of 1.3 nM. CGS 20625 can be used for the research of pentylenetetrazol-induced seizures[1].

Target Antigen

GABA Receptor

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cgs-20625.html

Purity

99.80

Solubility

DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

O=C1C2=CNC(CCCCC3)=C3C2=NN1C4=CC=C(OC)C=C4

Molecular Weight

309.36

References & Citations

[1]Williams M, et al. CGS 20625, a novel pyrazolopyridine anxiolytic. J Pharmacol Exp Ther. 1989 Jan;248(1):89-96.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-106316/CGS-20625-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-106316/CGS-20625-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

111205-55-1

Available Sizes

Curated Selection

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