Cabotegravir (sodium)
Cabotegravir (GSK-1265744) sodium is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 (OAT1/OAT3) inhibitor with IC50 values of 2.5 nM, 0.41 μM and 0.81 μM for HIVADA, OAT3 and OAT1, respectively. Cabotegravir sodium is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs) . Cabotegravir sodium can be used to research AIDS[1][2].
Product Specifications
CAS Number
1051375-13-3
Product Name Alternative
GSK-1265744 (sodium) ; S/GSK1265744 (sodium)
UNSPSC
12352005
Hazard Statement
H400, H410
Target
HIV; HIV Integrase; OAT
Type
Reference compound
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cabotegravir-sodium.html
Purity
99.87
Solubility
DMSO : 6.25 mg/mL (ultrasonic)
Smiles
FC1=C(CNC(C2=CN3C(C(N([C@@H](C)CO4)[C@@]4([H])C3)=O)=C(O[Na])C2=O)=O)C=CC(F)=C1
Molecular Formula
C19H16F2N3NaO5
Molecular Weight
427.33
Precautions
H400, H410
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
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