Carabersat
Carabersat is a potent anticonvulsant agent.
Product Specifications
CAS Number
184653-84-7
Product Name Alternative
SB-204269
UNSPSC
12352005
Target
Potassium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Carabersat.html
Concentration
10mM
Purity
98.22
Solubility
DMSO : 200 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H]1[C@@H](O)C(C)(C)OC2=CC=C(C(C)=O)C=C12)C3=CC=C(F)C=C3
Molecular Formula
C20H20FNO4
Molecular Weight
357.38
References & Citations
[1]Wai N. Chan, et al. Synthesis of Novel trans-4- (Substituted-benzamido) -3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile. J. Med. Chem., 1996, 39 (23), pp 4537-4539.|[2]Herdon H, et al. The novel anticonvulsant SB 204269 binds to a stereospecific site in the mouse brain. Eur J Pharmacol. 1996 Oct 31;314 (3) :R7-8.|[3]Caeser M, et al. Lack of effect of the novel anticonvulsant SB-204269 on voltage-dependent currents in neurones cultured from rat hippocampus. Neurosci Lett. 1999 Aug 13;271 (1) :57-60.|[4]Crespi F, et al. SB-204269 SmithKline Beecham. IDrugs. 1998 Sep;1 (5) :595-8.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
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