Carabersat

Carabersat is a potent anticonvulsant agent.

Product Specifications

CAS Number

[184653-84-7]

Product Name Alternative

SB-204269

UNSPSC

12352005

Target

Potassium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Carabersat.html

Concentration

10mM

Purity

98.22

Solubility

DMSO : 200 mg/mL (ultrasonic)

Smiles

O=C(N[C@@H]1[C@@H](O)C(C)(C)OC2=CC=C(C(C)=O)C=C12)C3=CC=C(F)C=C3

Molecular Formula

C20H20FNO4

Molecular Weight

357.38

References & Citations

[1]Wai N. Chan, et al. Synthesis of Novel trans-4- (Substituted-benzamido) -3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile. J. Med. Chem., 1996, 39 (23), pp 4537-4539.|[2]Herdon H, et al. The novel anticonvulsant SB 204269 binds to a stereospecific site in the mouse brain. Eur J Pharmacol. 1996 Oct 31;314 (3) :R7-8.|[3]Caeser M, et al. Lack of effect of the novel anticonvulsant SB-204269 on voltage-dependent currents in neurones cultured from rat hippocampus. Neurosci Lett. 1999 Aug 13;271 (1) :57-60.|[4]Crespi F, et al. SB-204269 SmithKline Beecham. IDrugs. 1998 Sep;1 (5) :595-8.