4- (Dimethylamino) phenol
4- (Dimethylamino) phenol is a potent cyanide antidote. 4- (Dimethylamino) phenol increases the extracellular lactate dehydrogenase (LDH) without markedly affecting gluconeogenesis. 4- (Dimethylamino) phenol cannot decreases the ATP content until the membrane becomes permeable to LDH. 4- (Dimethylamino) phenol’s toxicity is related to its reaction with glutathione and formation of covalent complexes, leading to impaired cellular function[1][2].
Product Specifications
CAS Number
[619-60-3]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/4-dimethylamino-phenol.html
Concentration
10mM
Purity
99.75
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
OC1=CC=C(N(C)C)C=C1
Molecular Formula
C8H11NO
Molecular Weight
137.18
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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