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PSB-1115

PSB-1115 is a selective A2B Adenosine Receptor antagonist. PSB-1115 inhibits the 2,4,6-trinitrobenzenesulfonic acid (TNBS) -induced contraction inhibition of acetylcholine (ACh) [1].

Product Specifications

CAS Number

152529-79-8

UNSPSC

12352005

Target

Adenosine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/psb-1115.html

Purity

99.0

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 10 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=S(C1=CC=C(C2=NC3=C(NC(N(CCC)C3=O)=O)N2)C=C1)(O)=O

Molecular Formula

C14H14N4O5S

Molecular Weight

350.35

References & Citations

[1]Michael S, et al. Adenosine A (2A) agonist and A (2B) antagonist mediate an inhibition of inflammation-induced contractile disturbance of a rat gastrointestinal preparation. Purinergic Signal. 2010 Mar;6 (1) :117-24.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Adenosine A2B receptor (A2BR)

Available Sizes

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