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CDK9-IN-12

CDK9-IN-12 displays the optimal CDK9 inhibitory activity with an IC50 value of 5.41 nM.

Product Specifications

CAS Number

1942843-54-0

Product Name Alternative

BL-5120,CD5789

UNSPSC

12352005

Target

CDK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cdk9-in-12.html

Purity

99.65

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

ClC1=C(C=C(C=N1)N[C@@H](CO)C2=CC=CC=C2)C3=CC=C(C4=C3)NN=C4C

Molecular Formula

C21H19ClN4O

Molecular Weight

378.85

References & Citations

[1]Han X, et al. Rational Design and Development of Novel CDK9 Inhibitors for the Treatment of Acute Myeloid Leukemia. J Med Chem. 2021 Oct 14;64 (19) :14647-14663.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CDK9

Available Sizes

Frequently Asked Questions

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