24-Norursodeoxycholic acid

24-norursodeoxycholic acid (Norucholic acid) is a side chain-shortened C23 homologue of UDCA and has shown potent anti-cholestatic, anti-inflammatory and anti-fibrotic properties.

Product Specifications

CAS Number

[99697-24-2]

Product Name Alternative

Norucholic acid; nor-UDCA

UNSPSC

12352211

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/24-Norursodeoxycholic_acid.html

Purity

99.68

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

C[C@H](CC(O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

Molecular Formula

C23H38O4

Molecular Weight

378.55

References & Citations

[1]Fickert P, et al. 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology. 2006 Feb;130 (2) :465-81.