ODN D-SL03 (sodium)
ODN D-SL03 sodium is a C class CpG oligonucleotides, and can induce stimulate PBMCs to produce high level of IFN-α. ODN D-SL03 sodium can activate human B cells, NK cells and mononuclear cells and up-regulate expression of CD80, CD86 and HLA-DR on the surface of subsets in human PBMCs. ODN D-SL03 sodium also can inhibit the growth of the tumor. ODN D-SL03 sequence: 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'[1].
Product Specifications
UNSPSC
12352208
Target
IFNAR
Type
Oligonucleotides
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/odn-d-sl03-sodium.html
Purity
98.57
Solubility
10 mM in H2O
Smiles
[ODND-SL03(sodium)]
Molecular Weight
9345 (free acid)
References & Citations
[1]Yang L, et al. CpG oligodeoxynucleotides with double stem-loops show strong immunostimulatory activity. Int Immunopharmacol. 2013 Jan;15 (1) :89-96.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
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