ODN D-SL03 (sodium)

ODN D-SL03 sodium is a C class CpG oligonucleotides, and can induce stimulate PBMCs to produce high level of IFN-α. ODN D-SL03 sodium can activate human B cells, NK cells and mononuclear cells and up-regulate expression of CD80, CD86 and HLA-DR on the surface of subsets in human PBMCs. ODN D-SL03 sodium also can inhibit the growth of the tumor. ODN D-SL03 sequence: 5'-tcgcgaacgttcgccgcgttcgaacgcgg-3'[1].

Product Specifications

UNSPSC

12352208

Target

IFNAR

Type

Oligonucleotides

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/odn-d-sl03-sodium.html

Purity

98.57

Solubility

10 mM in H2O

Smiles

[ODND-SL03(sodium)]

Molecular Weight

9345 (free acid)

References & Citations

[1]Yang L, et al. CpG oligodeoxynucleotides with double stem-loops show strong immunostimulatory activity. Int Immunopharmacol. 2013 Jan;15 (1) :89-96.