Fucosterol
Product Specifications
UNSPSC Description
Fucosterol is a sterol isolated from algae, seaweed or diatoms. Fucosterol exhibits various biological activities, including antioxidant, anti-adipogenic, blood cholesterol reducing, anti-diabetic and anti-cancer activities[1][2]. Fucosterol regulates adipogenesis via inhibition of PPARα and C/EBPα expression and can be used for anti-obesity agents development research[1].
Target Antigen
Endogenous Metabolite; PARP
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage;Epigenetics;Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/fucosterol.html
Purity
98.27
Solubility
DMSO : < 1 mg/mL|Ethanol : 16.67 mg/mL (ultrasonic)
Smiles
C/C=C(C(C)C)/CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC=C4CC(O)CC[C@]4(C)[C@@]3([H])CC[C@]12C
Molecular Weight
412.69
References & Citations
[1]Jung HA, et al. Anti-adipogenic activity of the edible brown alga Ecklonia stolonifera and its constituent fucosterol in 3T3-L1 adipocytes. Arch Pharm Res. 2014 Jun;37(6):713-20.|[2]Lee YS, et al. Anti-diabetic activities of fucosterol from Pelvetia siliquosa. Arch Pharm Res. 2004 Nov;27(11):1120-2.|[3]Khanavi M, et al. Cytotoxicity of fucosterol containing fraction of marine algae against breast and colon carcinoma cell line. Pharmacogn Mag. 2012 Jan;8(29):60-4.|[4]Caamal-Fuentes E, et al. Cytotoxic and antiproliferative constituents from Dictyota ciliolata, Padina sanctae-crucis and Turbinaria tricostata. Pharm Biol. 2014 Oct;52(10):1244-8.|[5]Qudeer Ahmed Abdul, et al. Health benefit of fucosterol from marine algae: a review. J Sci Food Agric. 2016 Apr;96(6):1856-66
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N4103/Fucosterol-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N4103/Fucosterol-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
17605-67-3
Available Sizes
Curated Selection
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