SMARCA2 Recombinant Rabbit Monoclonal Antibody [PSH01-15]
Probable global transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene. The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.
Product Specifications
Product Name Alternative
Abbreviation
SMARCA2, BAF190B, BRM, SNF2A, SNF2L2
Swiss Prot
P51531 Human
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human,Monkey
Immunogen
Synthetic peptide within human SMARCA2 aa 231-280 / 1,590.
Isotype
IgG
Clone
PSH01-15
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
Concentration
1 mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:200 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 181 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
CAS Number
9000-83-3
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