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SMARCA2 Recombinant Rabbit Monoclonal Antibody [PSH01-15]

Probable global transcription activator SNF2L2 is a protein that in humans is encoded by the SMARCA2 gene. The protein encoded by this gene is a member of the SWI/SNF family of proteins and is highly similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. Two transcript variants encoding different isoforms have been found for this gene, which contains a trinucleotide repeat (CAG) length polymorphism.

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

ATP dependent helicase SMARCA2 antibody ATP-dependent helicase SMARCA2 antibody BAF190 antibody BAF190B antibody BRG1-associated factor 190B antibody BRM antibody FLJ36757 antibody Global transcription activator homologous sequence antibody hBRM antibody hSNF2a antibody MGC74511 antibody Possible global transcription activator SNF2L2 antibody Probable global transcription activator SNF2L2 antibody Protein brahma homolog antibody SMARCA2 antibody SMCA2_HUMAN antibody SNF2 alpha antibody SNF2 like 2 antibody SNF2-alpha antibody SNF2/SWI2 like protein 2 antibody SNF2L2 antibody SNF2LA antibody Sth1p antibody Sucrose nonfermenting 2 like protein 2 antibody SWI/SNF related matrix associated actin dependent regulator of chromatin subfamily A member 2 antibody SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2 antibody

Abbreviation

SMARCA2, BAF190B, BRM, SNF2A, SNF2L2

Swiss Prot

P51531 Human

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Monkey

Immunogen

Synthetic peptide within human SMARCA2 aa 231-280 / 1,590.

Isotype

IgG

Clone

PSH01-15

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

HeLa cell lysate, HepG2 cell lysate, A549 cell lysate, MCF7 cell lysate, COS-1 cell lysate, human colon carcinoma tissue, human prostate carcinoma tissue, MCF7.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:200 ;FC: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 181 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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