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Afimkibart

Afimkibart (PF-06480605) is a human IgG1 monoclonal antibody targeting tumor necrosis factor-like ligand 1A (TL1A) . Afimkibart can be used in the research of inflammatory bowel disease[1].

Product Specifications

CAS Number

2911580-96-4

Product Name Alternative

PF-06480605; RVT-3101

UNSPSC

12352203

Target

TNF Receptor

Type

Inhibitory Antibodies

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/afimkibart.html

Purity

99.59

Smiles

[Afimkibart]

Molecular Weight

(146.54 kDa)

References & Citations

[1]Danese S, et al. Anti-TL1A antibody PF-06480605 safety and efficacy for ulcerative colitis: a phase 2a single-arm study[J]. Clinical Gastroenterology and Hepatology, 2021, 19 (11) : 2324-2332. e6.

Shipping Conditions

Dry Ice

Storage Conditions

Store at -80°C for 2 years

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 2

Available Sizes

Frequently Asked Questions

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