Afimkibart
Afimkibart (PF-06480605) is a human IgG1 monoclonal antibody targeting tumor necrosis factor-like ligand 1A (TL1A) . Afimkibart can be used in the research of inflammatory bowel disease[1].
Product Specifications
CAS Number
[2911580-96-4]
Product Name Alternative
PF-06480605; RVT-3101
UNSPSC
12352203
Target
TNF Receptor
Type
Inhibitory Antibodies
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/afimkibart.html
Purity
99.59
Smiles
[Afimkibart]
Molecular Weight
(146.54 kDa)
References & Citations
[1]Danese S, et al. Anti-TL1A antibody PF-06480605 safety and efficacy for ulcerative colitis: a phase 2a single-arm study[J]. Clinical Gastroenterology and Hepatology, 2021, 19 (11) : 2324-2332. e6.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Available Sizes
Curated Selection
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