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Fmoc-D-Val-D-Cit-PAB

Fmoc-D-Val-D-Cit-PAB is a cleavable linker for antibody-agent-conjugation (ADC) [1].

Product Specifications

CAS Number

1350456-69-7

UNSPSC

12352203

Hazard Statement

H302-H315-H319-H335

Target

ADC Linker

Type

ADC Related

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fmoc-d-val-d-cit-pab.html

Purity

98.97

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OCC(C=C1)=CC=C1NC([C@@H](CCCNC(N)=O)NC([C@@H](C(C)C)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=O)=O

Molecular Formula

C33H39N5O6

Molecular Weight

601.69

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Peter D. Senter, et al. Drug conjugates and their use for treating cancer, an autoimmune disease or an infectious disease.WO2004010957A2.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

ADC Related

Clinical Information

No Development Reported

Isoform

Protease Cleavable Linker

Available Sizes

Frequently Asked Questions

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