HOPan
HOPan is a PanK substrate and Pantothenate (HY-B0430) analog. HOPan inhibits CoA levels[1][2].
Product Specifications
CAS Number
[18679-90-8]
UNSPSC
12352211
Hazard Statement
H302, H315, H319
Target
Drug Derivative; PANK
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; Others
Applications
COVID-19-immunoregulation
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hopan.html
Purity
99.83
Solubility
H2O : 100 mg/mL (ultrasonic)
Smiles
OCC(C)(C)[C@@H](O)C(NCCCC(O)=O)=O
Molecular Formula
C10H19NO5
Molecular Weight
233.26
Precautions
H302, H315, H319
References & Citations
[1]Mostert KJ, et al. The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity. ACS Chem Biol. 2021 Nov 19;16 (11) :2401-2414. |[2]Ma Y, et al. Highly selective DNA aptamer sensor for intracellular detection of coenzyme A. Chem Sci. 2025 Mar 28;16 (18) :8023-8029.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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