Dalutrafusp alfa

Dalutrafusp alfa (AGEN-1423; GS-1423) is a specific bifunctional antibody against CD73 and TGF-β, which is involved in the immunosuppressive pathway[1].

Product Specifications

CAS Number

[2419918-89-9]

Product Name Alternative

AGEN-1423; GS-1423

UNSPSC

12352203

Target

CD73; TGF-β Receptor

Type

Inhibitory Antibodies

Related Pathways

Immunology/Inflammation; TGF-beta/Smad

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Cancer

Assay Protocol

https://www.medchemexpress.com/dalutrafusp-alfa.html

Purity

96.83

Solubility

10 mM in DMSO

Smiles

[Dalutrafuspalfa]

Molecular Weight

(178.15 kDa)

References & Citations

[1]Anthony W Tolcher, et al. Phase 1 first-in-human study of dalutrafusp alfa, an anti-CD73-TGF-β-trap bifunctional antibody, in patients with advanced solid tumors. J Immunother Cancer. 2023 Feb;11 (2) :e005267.