DMTr-LNA-5MeU-3-CED-phosphoramidite

DMTr-LNA-5MeU-3-CED-phosphoramidite is a nucleoside derivative[1].

Product Specifications

CAS Number

[206055-75-6]

UNSPSC

12352005

Hazard Statement

H315, H319

Target

DNA/RNA Synthesis; Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/DMTr-LNA-5MeU-3-CED-phosphoramidite.html

Concentration

10mM

Purity

98.75

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

CC(C)N(C(C)C)P(OCCC#N)O[C@H]1[C@@H](OC2)[C@H](N3C(NC(C(C)=C3)=O)=O)O[C@]12COC(C4=CC=CC=C4)(C5=CC=C(OC)C=C5)C6=CC=C(OC)C=C6

Molecular Formula

C41H49N4O9P

Molecular Weight

772.82

Precautions

H315, H319

References & Citations

[1]Kumar P, et al. Locked nucleic acid (LNA) enhances binding affinity of triazole-linked DNA towards RNA. Chem Commun (Camb) . 2017 Aug 3;53 (63) :8910-8913.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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