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Tacrine (hydrochloride) (hydrate) (Standard)

Tacrine (hydrochloride) (hydrate) (Standard) is the analytical standard of Tacrine (hydrochloride) (hydrate) . This product is intended for research and analytical applications. Tacrine hydrochloride (hydrate) is an inhibitor of both acetyl (AChE) and butyryl-cholinestrase (BChE) with IC50s of 31 nM and 25.6 nM, respectively.

Product Specifications

CAS Number

206658-92-6

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Reference Standards

Type

Reference Standards

Related Pathways

Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/tacrine-hydrochloride-hydrate-standard.html

Smiles

NC1=C(CCCC2)C2=NC3=CC=CC=C31.[H]Cl.[H]O[H].[x].[x]

Molecular Formula

C13H14N2.xHCl.xH2O

References & Citations

[1]Ahmed M, et al. Inhibition of two different cholinesterases by tacrine. Chem Biol Interact. 2006 Aug 25;162 (2) :165-71.|[2]Grasing K, et al. Enduring effects of tacrine on cocaine-reinforced behavior: Analysis by conditioned-place preference, temporal separation from drug reward, and reinstatement. Pharmacol Res. 2015 Jul;97:40-7.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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