MARK4 inhibitor 3
MARK4 inhibitor 3 (compound 23b) is an inhibitor of MARK4 with an IC50 value of 1.01 μM. MARK4 inhibitor 3 inhibits cancer cells growth. MARK4 inhibitor 3 can be used for research on cancer and tauopathies[1].
Product Specifications
UNSPSC
12352005
Target
MARK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mark4-inhibitor-3.html
Purity
98.23
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC=C(F)C=C1)[C@@H](NC(CN(C2=C3C=CC=C2)C4=CC=C(C)C=C4C3=O)=O)CC5=CNC6=C5C=CC=C6
Molecular Formula
C33H27FN4O3
Molecular Weight
546.59
References & Citations
[1]Maria Voura, et al. Synthesis, Structural Modification, and Bioactivity Evaluation of Substituted Acridones as Potent Microtubule Affinity-Regulating Kinase 4 Inhibitors. ACS Pharmacology & Translational Science 2023 6 (7), 1052-1074.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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